Each ml contains:
Oxytetracycline Dihydrate B.P
Eq. to Oxytetracycline.............…...200 mg
Vehicle ...................................................q.s.

Oxytetracycline is known as a broad-spectrum antibiotic due to its activity against such a wide range of infections. It was the second of the tetracyclines to be
discovered. Oxytetracycline, like other tetracyclines, is used to treat many infections common and rare. Its better absorption prole makes it preferable to tetracycline for moderately severe acne, but alternatives sould be sought if no improvement occurs by 3 months.

Mechanism of action:
Oxytetracycline inhibits cell growth by inhibiting translation. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic and can easily pass through the cell membrane or passively diffuses through porin channels in the bacterial membrane.
Pharmacological Classification: 80.22.11 Broad and medium spectrum antibiotics
Physical form: Solution for injection
Colour: Brownish yellow coloured liquid

Gastrointestinal, respiratory and reproductive tract infections caused by oxytetracycline sensitive microorganisms, like Bordetella, Campylobacter,
Chlamydia, E. coli, Haemophilus, Mycoplasma, Pasteurella, Rickettsia, Salmonella, Staphylococcus and Streptococcus spp. in cattle, goats, sheep and pigs.
For the treatment of Pasteurellosis, pneumonia, metritis, pyometra, mastitis, keratoconjunctivitis (pink-eye) and foot rot. 
Sheep: Pneumonia and bacterial dysentery.
Pigs: Pneumonia caused by Pasteurella organisms and MMA complex.

Dosage and Administration:
ASHOXY 20% LA should be administered by deep intramuscular injection at the dose rate of 20 mg/kg body weight (1 ml of ASHOXY 20% LA per 10 kg body weight). In cattle not more than 10 ml, and in sheep and pigs not more than 5 ml to be given at any one site. In pigs weighing less than 10 kg a maximum of 1 ml should be used. “Treatment should be repeated 3 to 4 days at 24 hours intervals. If there is no response to t r e a t m e n t , t h e d i a g n o s i s a n d t h e r a p y s h o u l d b e r e v i e w e d a f t e r 4 8 h o u r s . " After withdrawal of first dose discard unused material

After withdrawal of first dose discard unused materials

Tetracyclines generally act as bacteriostatic antibiotics and inhibit protein synthesis by reversibly binding to 30S ribosomal subunits of susceptible organisms, thereby preventing binding to those ribosomes of aminoacyl transfer-RNA. Tetracyclines also are believed to reversibly bind to 50S ribosomes and additionally alter cytoplasmic membrane permeability in susceptible organisms. In high concentrations, tetracyclines can also inhibit protein synthesis by mammalian cells.

Not recommended for cats, dogs, horses and donkeys. The use of this product during the period of tooth development including late pregnancy may
lead to tooth discoloration.

Oxytetracycline may interact with other medications, such as oral antacids

Side Effects:
Oxytetracycline and tetracycline given to young animals can cause discoloration of teeth to a yellow or brown colour. High dosages or chronic administration may delay bone growth and healing. Tetracyclines can some time cause nausea, vomiting, anorexia and diarrhoea.

Withdrawal Period:
Cattle : Meat - 31 days Milk - 10 days
Sheep : Meat - 28 days
Pig : 35 days
Not for use in ewes producing milk for human consumption.

Store below 30°C in a dry place, protect from direct sunlight.

30 ml, 50 ml and 100 ml